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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0406
All Species:
15.76
Human Site:
S463
Identified Species:
38.52
UniProt:
O43156
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43156
NP_055472.1
1089
122069
S463
L
N
A
S
P
K
T
S
A
T
Q
P
W
N
R
Chimpanzee
Pan troglodytes
XP_514634
1089
121903
S463
L
N
A
S
P
K
T
S
A
T
Q
P
W
N
C
Rhesus Macaque
Macaca mulatta
XP_001090176
1089
122101
S463
L
N
A
S
P
K
T
S
A
T
Q
P
W
N
H
Dog
Lupus familis
XP_534416
1097
122026
A468
P
L
G
A
S
E
T
A
A
T
Q
P
R
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91V83
1085
120824
S463
L
S
A
S
A
E
V
S
A
A
R
P
W
S
R
Rat
Rattus norvegicus
NP_001128091
1088
121092
S463
L
S
A
S
A
E
A
S
A
A
R
P
W
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234099
1094
120916
Q462
Y
D
P
S
G
S
V
Q
H
G
V
Q
K
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698602
1079
120278
R460
L
T
S
S
A
D
L
R
P
D
V
Q
Q
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120334
724
83764
H157
K
E
L
V
E
T
I
H
L
L
L
T
S
Y
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199584
616
69630
R48
D
S
V
S
A
R
L
R
H
Y
E
W
N
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.2
N.A.
84.7
84.9
N.A.
N.A.
60.9
N.A.
54.4
N.A.
N.A.
22.1
N.A.
22.6
Protein Similarity:
100
99.3
98.3
92.3
N.A.
91.8
92.5
N.A.
N.A.
77.1
N.A.
70.4
N.A.
N.A.
40.3
N.A.
34.1
P-Site Identity:
100
93.3
93.3
33.3
N.A.
53.3
53.3
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
60
N.A.
80
80
N.A.
N.A.
20
N.A.
20
N.A.
N.A.
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
10
40
0
10
10
60
20
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
10
0
0
0
10
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
10
0
0
10
30
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
20
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
10
0
0
0
0
30
0
0
0
0
0
0
10
0
10
% K
% Leu:
60
10
10
0
0
0
20
0
10
10
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
30
0
0
0
0
0
0
0
0
0
0
10
30
0
% N
% Pro:
10
0
10
0
30
0
0
0
10
0
0
60
0
0
20
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
40
20
10
0
0
% Q
% Arg:
0
0
0
0
0
10
0
20
0
0
20
0
10
0
40
% R
% Ser:
0
30
10
80
10
10
0
50
0
0
0
0
10
30
0
% S
% Thr:
0
10
0
0
0
10
40
0
0
40
0
10
0
0
0
% T
% Val:
0
0
10
10
0
0
20
0
0
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
50
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _